Poorly tuned neuronal communication may underlie neurological and psychiatric disease

(JCI Journals) In this issue of the JCI, Nils Brose and colleagues at the Max Planck Institute for Experimental Medicine have identified a mutation in a synaptic protein called UNC13 in a patient diagnosed with ASD, hyperactivity, and dyskinesia. Further investigation revealed that the UNC13 mutation disturbs the fine-tuning of neuronal communication at the level of the synapse.

from EurekAlert! - Social and Behavioral Science http://ift.tt/2lDfIEF