(Elsevier) The hypocretin/orexin (HCRT) system of the brain is best known for promoting wakefulness and appetite. A new paper in Biological Psychiatry suggests that blocking hypocretin signaling via the HCRT-1 receptor (HCRT-R1) might also reduce the appetite for cocaine. The study, led by first author Dr. Brooke Schmeichel in George Koob's laboratory at the National Institute on Drug Abuse (NIDA), Intramural Research Program, Baltimore, Maryland, suggests that blocking hypocretin signaling may provide a new avenue for treating cocaine addiction.
from EurekAlert! - Social and Behavioral Science http://ift.tt/2mvZUQ1
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