Leptomeningeal metastases more common in NSCLC patients with EGFR mutations

(International Association for the Study of Lung Cancer) Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. Patients receiving tyrosine kinase inhibitors (TKIs) targeting EGFR mutations had a longer overall survival (OS) than those who did not receive TKIs, demonstrating the effectiveness of TKIs for LM therapy.

from EurekAlert! - Social and Behavioral Science http://ift.tt/2aWRY7W