Defining immortality of stem cells to identify novel anti-aging mechanisms

(University of Cologne) With age, somatic cells such as neurons lose their ability to maintain the quality of their protein content. Pluripotent stem cells, on the contrary, do not age and have increased mechanism to maintain the integrity of their proteins. Researchers from CECAD, the Cluster of Excellence on Aging Research based at the University of Cologne, defined the mechanisms underlying increased protein quality control of pluripotent stem cells. Their research was published in Nature Communications on Nov. 28.

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