A molecular pit crew responsible for refuelling in signaling cells

(National Centre for Biological Sciences) Raghu Padinjat's group from the National Centre for Biological Sciences (NCBS), Bangalore, has identified a molecular pit crew that helps to refuel signaling cells efficiently. Researchers from the group have shown that three proteins--the enzyme PI4KIIIα (phosphatidylinositol 4-kinase IIIα), and two other proteins, Efr3 and TTC7-- are crucial for maintaining levels of the lipid molecule PIP2 (phosphatidylinositol 4,5- bisphosphate), on the surface membranes of cells, where it is vital for producing molecular messengers during cellular signaling.

from EurekAlert! - Social and Behavioral Science https://ift.tt/2Mx9h3B