(American Psychiatric Association) A new study appearing online today from the American Journal of Psychiatry finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action. While opioids have been used historically to treat depression, they are known to carry a high risk of dependence.
from EurekAlert! - Social and Behavioral Science https://ift.tt/2NrGIB6
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