Multiple genetic markers combined to estimate risk of developing Alzheimer's disease

(PLOS) A risk score derived from genetic data may be able to estimate an individual's risk of Alzheimer's disease at a particular age, according to research published in PLOS Medicine. The polygenic hazard score (PHS) was developed by Rahul Desikan, of the University of California, San Francisco, USA, and colleagues, using genotype data from three large cohorts (totaling over 70,000 individuals) of patients with Alzheimer's disease (AD) and normal elderly individuals.

from EurekAlert! - Social and Behavioral Science http://ift.tt/2mpIcSS