Searching for the origins of the depressive symptoms in Huntington's disease

(University of Barcelona) About 40% of the affected patients with Huntington's disease -- a neurodegenerative pathology -- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease. An altered function of Cdk5 kinase -- an essential enzyme in several cell signalling pathways -- could explain the physiopathology of the depressive-like behaviour in Huntington's disease.

from EurekAlert! - Social and Behavioral Science http://bit.ly/2WghpdD