(Bentham Science Publishers) 5-hydroxytryptamine subtype 6 receptor (5-HT6R) has been extensively considered as a promising therapeutic target for the treatment of neuropathological disorders. 5-HT6R were hypothesized to be implicated in the processes of learning, memory retention, and cognition. Several selective 5-HT6R ligands are currently undergoing clinical trials for treatment of Alzheimer's disease and schizophrenia, SB-742457 and Lu-AE-58054.
from EurekAlert! - Social and Behavioral Science http://ift.tt/2kwP2VP
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